郭育綺老師

郭育綺老師

職稱: 
教授
辦公室位置: 
104年1月辭世
學歷: 
輔仁大學生物系學士
清華大學分子生物研究所碩士
陽明大學微生物及免疫研究所博士
專長: 
病毒學
中草藥藥理學
免疫藥理學
病毒藥理學
研究概況: 
病毒學
中草藥藥理學
免疫藥理學
病毒藥理學
研究方向: 
中草藥抽出物之抗病毒活性與作用機轉研究
中草藥抽出物之免疫調控活性研究

期刊論文

  1. Zhu Y、Pettolino F、Mau SL、Shen YC、Chen CF、Kuo YC、Basic A,「Immunoactive polysaccharide-rich fractions from Panax notoginseng.」,Planta medica72卷,期(2006-12-01):1-7(SCI)
  2. Wang WY、Liu CP、Kuo YC、Lin YL,「Anti-lymphoproliferative alkaloids from Plumula Nelumbinis」,The Chinese Pharmaceutical J.56卷,期(2004-11-01):25-30()
  3. Lee TH,、Lee SS,、Kuo YC,、Chou CH.,「Monoterpene glycosides and triterpene acids from Eribotrya deflexa.」,J. Nat. Prod.64卷,期(2001-01-01):865-869()
  4. Lin LC,、Chou CJ,、Kuo YC.,「Cytotoxic principles from Ventilago leiocarpa.」,J. Nat. Prod.64卷,期(2001-01-01):674-676()
  5. Kuo YC,、Chen CC,、Tsai WJ,、Ho YH.,「Regulation of herpes simpelx virus type 1 replication in Vero cells by Psycotria serpens. Relationship to genes expression, DNA replication, and proteins synthesis.」,Antivir. Res.51卷,期(2001-01-01):95-109()
  6. Kuo YC,、Lin YL,、Liu CP,「Herpes simplex virus type 1 propagation in HeLa cells interrupted by Nelumbo nucifera .」,J. Biomedical Sciences12卷,6期(2005-12-01):1021-1034(SCI)
  7. Chang MS、Yang YC、Kuo YC、Kuo YH、Lee TH,「Furocoumarin glycosides from the leaves of Ficus ruficaulis Merr. var. antaoenisis」,J. Nat. Prod.68卷,期(2005-01-01):11-13(SCI)
  8. Kuo YC,、Meng HC,、Tsai WJ.,「Regulation of cell proliferation, inflammatory cytokines production and calcium mobilization in primary human T lymphocytes by emodin from Polygonum hypoleucum Ohwi.」,Inflamm. Res.50卷,期(2001-01-01):73-82()
  9. Kuo YC,、Tsai WJ,、Wang JY,、Chang SC, Lin CY,、Shiao MS.,「Regulation of bronchoalveolar lavage fluid cells functions by the immunomodulatory agents from Cordyceps sinensis.」,Life Sci.68卷,期(2001-01-01):1067-1082()
  10. Kuo YC,、Tsai WJ,、Meng HS,、Chen WP,、Yang LY, and Lin CY.,「Blocking of cell proliferation following administration of an anthraquinone isolated from Polygonum hypoleucum Ohwi in the human mesangial cells. Relationship to cytokines production, genes expression, and calcium mobilization.」,Life Sci.68卷,期(2001-01-01):1271-1286()
  11. Tsai TF,、 Hiseh CH,、Lin YS,、Tsai WJ,、Kuo YC.,「Enhancement of cell proliferation and cytokines production in human peripheral blood mononuclear cells by extracts from blood-enriching dang-gui decoction.」,J. Chinese Med.12卷,期(2001-01-01):191-202()
  12. Kuo YC、Tsai WJ、Meng HC、Chen WP、Yang LY,「Immune responses in human mesangial cells regulated by emodin from Polygonum hypoleucum ohwi」,Life Sciences68卷,期(2001-01-01):1271-1286(SCI)
  13. Kuo YC,、Lin YL,、 Huang CP,、Shu JW,、Tsai WJ.,「A tumor cell growth inhibitor from Saposhnikovae divaricata.」,Cancer Invest.20卷,期(2002-01-01):7-11()
  14. Weng SC,、Chou CJ,、Lin LC,、Tsai WJ,、Kuo YC.,「Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae.」,J. Ethnopharmacol.83卷,期(2002-01-01):79-85()
  15. Kuo YC,、Huang YL,、Chen CC,、Lin YZ, Chung KA,、Tsai WJ.,「Cell cycel progression and cytokine genes expression of human blood mononuclear cells modulated by Agaricus blazei.」,J. Lab. Clin. Med.140卷,期(2002-01-01):176-187()
  16. Lin LC,、Kuo YC,、Chou CJ.,「Immunomodulatory Proanthocyanidins from Ecdysanthera utilis.」,J. Nat. Prod.65卷,期(2002-01-01):505-508()
  17. Shen CC、Kuo YC、Huang RL、Lin LC、Chou CJ,「New ergostane and lanostane from Antrodia Camphorata」,J. Chinese Medicine14卷,期(2003-01-01):247-258()
  18. Lee TH,、Kuo YC,、Wang GJ,、Kuo YH, Chang CI,、Lee CK,and Lee CK.,「Five new phenolics from the roots of Ficus beecheyana.」,J. Nat. Prod.卷,期(2002-01-01):1497-1500(SCI)
  19. Kuo YC,、Lin LC,、Yang NS,、Tsai WJ, 、Lin AP,、Lee MJ,、Chou CJ.,「Some immunomodulatory principles isolated from Piper kadsura.」,J. Chinese. Med.13卷,期(2002-01-01):159-170()
  20. Kuo YC,、Lin LC,、Tsai WJ,、Chou CJ, 、Kung SH,、Ho YH.,「Samaragenin B identified from Limonium sinense suppressed herpes simplex virus type 1 replication in Vero cells by regulation of viral macromolecular synthesis.」,Antimicrob. Agents Ch.46卷,期(2002-01-01):2854-2864()
  21. Kuo YC,、Lin AP,、Lee MJ,、Chou CJ,、Fan CY, and Tsai WJ.,「Inhibitory effects of extracts from Vandellia cordifolia on tumor cells proliferation.」,J. Chinese Med.卷,期(2003-01-01):163-174()
  22. Kuo YC、Yang LM、Lin LC,「Isolation and immunomodulatory effect of flavonoids from Syzygium samaragenese」,Planta Medica70卷,期(2004-07-01):1237-1239(SCI)
  23. Kuo YC,、Weng SC,、Chou CJ,、Chang TT,、Tsai WJ.,「Activation and proliferation signals in primary human T lymphocytes inhibited by ergosterol peroxide isolated from Cordyceps cicadae.」,Br. J. Pharmacology140卷,期(2003-01-01):895-906()
  24. Kuo YC,、Lin LC,、Don MJ,、Liao HF, Tsai YP,、Lee GH, and Chou CJ.,「Cyclodesipeptide and dioxomorpholine derivatives isolated from insect-body portion of the fungus Cordyceps cicadae.」,J. Chinese Med.13卷,期(2002-01-01):209-219()
  25. Liu CP,、Kuo YC,、Liao JF,、Chen CF,、Tsai WJ.,「Effects of platelet-activating factor on cyclooxygenase-2 gene expression in human polymorphonuclear neutrophils modulated by temperature.」,Analytical Pharmacology4卷,期(2003-01-01):48-53()
  26. Liu CP,、Tsai WJ,、Lin YL,、Liao JF,、Chen CF, and Kuo YC.,「The extracts from Nelumbo nucrifera suppress cell cycle progression, cytokine genes expression, and cell proliferation in human peripheral blood mononuclear cells.」,Life Sci.75卷,期(2004-01-01):699-716(SCI)
  27. Tsai WJ、Lin YL、Ho YC、Kuo YC,「Inhibition of cyclic AMP phosphodiesterase and blockage of arachidonate metabolism by antiplatelet principles from the seed Hulls of Arachis hypogaea L.」,The Chinese Pharmaceutical J.55卷,期(2003-03-01):335-345()
  28. Kuo YC、Lu CK、Huang LW、Kuo YH、Lee TH,「Inhibitory effects of acylated kaempferol glycosides from the leaves of Cinnamomum kotoense on the proliferation of human peripheral blood mononuclear cells.」,Planta Medica71卷,5期(2005-05-01):412-415(SCI)
  29. Chih-Peng Liu、Yuh-Chi Kuo、Chien-Chang Shen、Ming-Hsi Wu、Jyh-Fei Liao、Yun-Lian Lin、Chieh-Fu Chen、Wei-Jern Tsai,「(S)-Armepavine Inhibits Human Peripheral Blood Mononuclear Cells Activation by Regulating Itk and PLCγ Activation in a PI3K-Dependent Manner」,Journal of Leukocyte Biology81卷,期(2007-05-01):1276-1286(SCI)
  30. Chen YC、Tsai WJ、Wu MH、Lin LC、Kuo YC,「Suberosin inhibits human peripheral blood mononuclear cells proliferation through the modulation of NF-AT and NF-κB transcription factors」,British Journal of Pharmacology150卷,期(2007-06-01):298-312(SCI)
  31. Liu CP、Tsai WJ、Lin YL、Liao JF、Kuo YC,「Inhibitory Effects of (S)-Armepavine from Nelumbo Nucifera on Autoimmune Disease of MRL lpr/lpr Mice.」,Eur. J. Pharmacol.531卷,期(2006-01-01):270-279(SCI)
  32. Kuo YC、Kuo YS、Lin YL、Tsai WJ,「Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression 」,Antiviral Research70卷,期(2006-03-01):112-120(SCI)
  33. Lee TH、Kuo YC、Wang GJ、Kuo YH、Lee CK,「Five new phenolics from the roots of Ficus beecheyana」,J. Nat. Prod.65卷,期(2002-01-01):1497-1500(SCI)
  34. Wu MH、Tsai WJ、Don MJ、Chen YC、Chen IS、Kuo YC,「Tanshinlactone A from Salvia miltiorrhiza Modulates Interleukin-2 and Interferon-γ Gene Expression」,Journal of Ethnopharmacology113卷,期(2007-08-01):210-217(SCI)
  35. Shen YC、Wu YR、Lin JJ、Lo KL、Kuo YC、Aahraf Taha Khalil,「Eight new diterpenoids from soft coral cespitlaria hypotenaculata」,Tetrahedron63卷,期(2007-08-01):10914-20(SCI)
  36. Lin YS、Chiou SH、Kuo YC,「Bioactive marine prostanoids from Octocoral clavularia viridis」,Chemistry & Biodiversity 5卷,期(2008-05-01):784-792(SCI)
  37. Tsai WJ、Chen YC、Kuo YC,「Seselin from Plumbago zeylanica Inhibits Phytohemagglutinin (PHA)-stimulated Cell Proliferation in Human Peripheral Blood Mononuclear Cells.」,J. Ethnopharmacol 119卷,期(2008-09-01):67-73(SCI)
  38. Kuo YC、Lee YC、Leu YL、Tsai WJ、Chang SC,「 Antiviral Research ; Impact factor 3.358」,Efficacy of Orally Administered Lobelia Chinensis Extracts on Herpes Simplex Virus Type 1 Infection 80卷,期(2008-11-01):206-212(SCI)
  39. Wang SJ、Chou SH、Kuo YC、Chou SS P、Tzeng WF、Leu CY、Huang RF S、Liew YF,「HDT-1, a new synthetic compound, inhibits glutamate release in rat cerebral cortex nerve terminals (synaptosomes).」,Acta Pharmacologica Sinica29卷,期(2008-11-01):1289-1295(SCI)
  40. Shen YC、Lo KL、Kuo YH、Kuo YC、Chen CH、Khalil AT,「Cespihypotins Q-V, Verticillene Diterpenoids From Cespitularia hypotentaculata」,J. Nat. Prod.71卷,期(2008-12-01):1993-1997(SCI)
  41. Chen YC、 Chang SC、Wu MH、Chuang KA、Wu JY、Tsai WJ、Kuo YC,「Norcantharidin reduced cyclins and cytokines production in human peripheral blood mononuclear cells」,Life Sciences84卷,期(2009-02-01):218-226(SCI)
  42. Chen PY、Kuo YC、Chen CH、Kuo YH、Lee CK,「Isolation and immunomodulatory effect of homoisoflavones and flavones from Agave sisalana Perrine ex Engelm.」,Molecules 14卷,期(2009-05-01):1789-1795(SCI)
  43. Cheng YB、Chang MT、Lo YW、Ho CJ、Kuo YC、Chien CT、Chen SY、Liou SS、Kuo YH、Shen YC,「Oxygenated lignans from the fruits of Schisadra arisanensis.」,J Nat. Prod.72卷,期(2009-07-01):1663-1668(SCI)
  44. Chuang CF、Abd EI-Razek MH、Kuo YC、Chien CT、Chou CH、Shen YC,「Taxane diterpenoids from Taiwanese yew Taxus sumatrana.」,Helv. Chim. Acta 92卷,期(2009-07-01):2134-2145(SCI)
  45. Cheng YB、Liao TC、Lo IW、Chen YC、Kuo YC、Chen SY、Chien CT、Shen YC,「Arisandilactone A, a new triterpenoid from the fruits of Schisandra arisanensis.」,Org Lett.12卷,期(2010-03-01):1016-1019(SCI)
  46. Kuo YJ、Yang YC、Zhang LJ、Wu MD、Kuo Yang LM、Kuo YC、Hwang SY、Chou CJ、Lee KH、Kuo YH,「Flavanone and diphenylpropane glycosides and glycosidic acyl esters from Viscum articulatum.」,J. Nat. Prod.73卷,期(2010-03-01):109-114(SCI)
  47. Chou SH、Chou SS、Liew YF、Leu JY、Wang SJ、Huang S RF、Tzeng WF、 Kuo YC,「A newly synthetic compound, 2-OH, enhances human peripheral blood Mononuclear cells proliferation.」,Molecules12卷,期(2009-07-01):2345-2355(SCI)
  48. Chou SC、Su CR、Kuo YC、Wu TS,「The constituents and their bioactives of Houttuynia cordata.」,Chem. Pharm. Bull. 57卷,期(2009-06-01):1227-1230(SCI)
  49. Chou SH、Chou SS、Liew YF、Leu JY、Wang SJ、Huang S RF、Tzeng WF、 Kuo YC,「One synthetic compound, HDT-1, inhibits human peripheral blood mononuclear cells proliferation.」, Fu Jen Studies Science and Engineering43卷,期(2009-12-01):161-174(其他)
  50. Cheng YB、Liao TC、Lo YW、Chen YC、Kuo YC、Chen SY、Chien CT、Hwang TL、Shen YC,「Nortriterpene lactomes from the fruits of Schisandra arisanensis.」,J. Nat. Prod.73卷,期(2010-06-01):1228-1233(SCI)
  51. Ka SM、Kuo YC、Ho PJ、Tsai PY、Hsu YJ、Tsai WJ、Lin YL、Shen CC、Chen A,「(S)-armepavine from Chinese medicine improves experimental autoimmune crescentic glomerulonephrits.」,Reumatol. 49卷,期(2010-06-01):1840-1851(SCI)
  52. Wu MH、Lee YC、Tsai WJ、Yang WB、Chen YC、Chuang KA、Liao JF、Wang CC、Kuo YC,「Characterized polysaccharides from black soybean induce granulocyte colony-stimulated factor gene expression in a phosphoinositide 3-kinase-dependent manner.」,Immunol. Invest.40卷,期(2011-01-01):39-61(SCI)
  53. Chunag KA、Lieu CH、Tsai WJ、Wu MH、Chen YC、Liao JF、Wang CC、Kuo YC,「Evaluation of anti-Wnt/β-catenin signaling agents by pGL4-TOP transfected stable cells with a luciferase reporter system.」, Brazilian J. Med. and Biol. Res.43卷,期(2010-09-01):931-941(SCI)
  54. Liew YF、Huang CT、Chou SS、Kuo YC、Chou SH、Leu JY、Tzeng WF、Wang SJ、Tang MC、Huang RF,「The isolated and combined effects of folic acid and synthetic bioactive compounds against Abeta(25-35)-induced toxicity in human microglial cells.」,Molecules15卷,期(2010-03-01):1632-1644(SCI)
  55. Tsai WJ、Chang CT、Wang GJ、Lee TH、Chang SF、Lu SC、Kuo YC,「Arctigenin from Arctium lappa inhibits interleukin-2 and interferon- gene expression in primary human T lymphocytes.」,Chinese Medicine6卷,期(2011-03-01):12-19(SCI)
  56. Kuo PC、Hwang TL、Lin YT、Kuo YC、Leu YL,「Chemical constitutents from Lobelia chinensis and their anti-virus and anti-inflammatory bioactivies.」,Arch Pharm Res卷,期(2011-06-01):(SCI)
  57. Lin TY、Lu CW、Huang SK、Chou SS、Kuo YC、Chou SH、Tzeng WF、Leu CY、Huang RF、Liew YF & Wang SJ,「HTDP-2, a new synthetic compound, inhibits glutamate release through reduction of voltage-dependent Ca²⁺ influx in rat cerebral cortex nerve terminals.」,Pharmacol. 88卷,期(2011-10-01):26-32(SCI)
  58. Tsai WJ、Yang SC、Huang YL、Chen CC、Chuang KA、Kuo YC,「4-Hydroxy-17-methylincisterol from Agaricus blazei decreased cytokines production and cells Proliferation in human peripheral blood mononuclear cells via inhibition of NF-AT and NF-B activation.」,Evid.-Based Compl. Alt. Med.卷,期(2013-02-01):(SCI)
  59. Chuang KA、Lieu CH、Tsai WJ、Huang WH、Lee AR、Kuo YC,「3-Methoxyapigenin modulates β-catenin stability and inhibits Wnt/β-catenin signaling in Jurkat leukemic cells.」,Life Sci.卷,期(2013-03-01):(SCI)

會議論文

  1. Lee YC、Tsai WJ、Yang HY、Kuo YC,「To Study the G-CSF Gene Expression in Human Peripheral Blood Mononuclear Cells Induced by Glycine max Extracts.」,,,,,2004-01-01
  2. Liu CP,、Kuo YC,、Chen CF,、Liao JF、Tsai WJ.,「Activation and proliferation signals in human peripheral blood mononuclear cells inhibited vy (S)-Armepavine isolated from Nelumbo nucifera.」,,,,,2004-04-01
  3. Yang SC,、Huang YL.,、Kuo YC.,,「Regulation of Cell Proliferation, Gene Expression, Production of Cytokines and Cell Cycle Progression in Human Peripheral Blood Mononuclear Cells by 4-Hydroxy-17-methylincisterol Isolated from Agaricus blazei.」,,,,,2004-04-01
  4. Kuo YC,「Regulation of herpes simplex virus type 1 replication in BALb/c mice by Chinese herbs extraction.」,,,,,2005-01-01
  5. Lee YC、Leu YL、Tsai WJ、Kuo YC,「Extracts from Lobelia chinensis Inhibit Herpes Simplex Virus Type 1 Infection」,,,,,2005-01-01
  6. Chuang KA、Lieu CH、Tsai WJ、Kuo YC,「Expression of severe acute respiratory syndrome-coronavirus S193 in Sf9 cells and establishment of a model for screening anti-viral drugs.」,天然藥物研討會,,,,2005-08-08
  7. Kuo YM、Lin LC、 Tsai WJ、 Kuo YC,「Gallomyricitrin from Syzygium samarangenses inhibits cell proliferation in human peripheral blood mononuclear cells induced by phytohemagglutinin.」,天然藥物研討會,,,,2005-08-08
  8. Yang ZY、Wang G.J、Tsai WJ、Kuo YC,「The Study of the inhibitory mechanism of arctigenin on platelet aggregation.」,生物醫學聯會,台北,中華民國,中華民國藥理學會,2006-04-01
  9. Lee PH、Tsai WJ、Chuang KA、Kuo YC,「Expression of SARS-Coronavirus spike proteins in Sf 9 cell line」,生物醫學聯會,台北,中華民國,中華民國藥理學會,2006-04-01
  10. Su DH、Tsai WJ、Kuo YC,「Evaluation of armepavine inhibiting inflammatory cytokines expression in rat mesangial cells induced by lipopolysaccharide」,生物醫學年會,台北,中華民國,中華民國藥理學會,2006-04-01
  11. Kuo YC,「(S)-Armepavine from Nelumbo nucifera Inhibits Autoimmune Disease of MRL/MpJ-lpr/lpr Mice and Its pharmacological Activity」,The International Symposium of Traditional Chinese Medicine Moderization,Taipei,Republic of China,,2006-09-01
  12. Kuo YC,、Chen CC,、Tsai WJ,、Ho YH.,「Regulation of herpes simpelx virus type 1 replication in Vero cells by Psycotria serpens. Relationship to genes expression, DNA replication, and proteins synthesis.」,,,,,2001-08-01
  13. Kuo YC,、Lin LC,、Tsai WJ,、Chou CJ,、Kung SH, and Ho YH.,「Samaragenin B identified from Limonium sinense suppresses herpes simplex virus type 1 replication in Vero cells by regulation of viral macromolecular synthesis.」,,,,,2002-10-01
  14. Kuo YC,、Weng SC,、Chou CJ,、Lin LC,、Tsai WJ.,「Activation and Proliferation Signals in Primary Human T lymphocytes Inhibited by Ergosterol Peroxide Isolated From Cordyceps cicadae.」,,,,,2002-11-01
  15. Chen YC,、Chen JF,、Lin LC,、Kuo YC.,「Regulation of cell proliferation and cytokine gene expression in human peripheral blood mononuclear cells by bioactive components from Plumbago zeylancia.」,,,,,2003-03-01
  16. Kuo YC,、Liu CP,、Liao JF,、Chen CF,、Tsai WJ.,「(S)-armepavine isolated from Nelumbo nucifera suppressed activation and proliferation in human peripheral blood mononulcear cells.」,,,,,2003-07-01
  17. Wu MH、 Tsai WJ、Liao JF、Kuo YC,「Study of immunomodulatory activities of black soybean polysaccharides in vivo.」,生物醫學年會,台北,中華民國,,2007-01-01
  18. Chen YC、 Liao JF、Chang SC、Kuo YC,「Regulation of cell proliferation and cytokine gene expression in human peripheral blood mononuclear cells by norcantharidin」,生物醫學年會,台北,中華民國,,2007-03-01
  19. Hsieh CC、Tsai WJ、Kuo YC,「Analysis of anti-herpes simplex virus type 1 activity from Roystonea regia extracts」,生物醫學聯合會議,Taipei,ROC,中華民國藥理學會,2008-03-22
  20. Chang CT、Tsai WJ、Kuo YC,「Study of natural products from Cinnamomum kotoense, Arctium lappa, and Agave sisalana regulation human T lymphocytes immune responses induced by anti-CD3 and Anti-CD28 antibodies.」,生物醫學聯合會議,Taipei,ROC,,2008-03-22
  21. Liao FU、Tsai WJ、Kuo YC,「Study of compounds from Cinnamomum kotoense, Agave sisalana, and Arctium lappa inhibiting inflammatory cytokines gene expression in rat mesangial cells induced by lipopolysaccaride.」,生物醫學聯合會議,Taipei,ROC,,2008-03-22
  22. Wu MH、Tsai WJ、Kuo YC,「Immunomodulatory Actions of Black Soybean Polysaccharides on BALB/c Mice and Its Bioactive Components.」,生物醫學聯會,Taipei,Taiwan,,2008-03-29
  23. Chen YC、Tsai WJ、Kuo YC,「Norcantharidin Inhibits Cell Cycle Progression and Cytokines Gene Expression in Human T Lymphocytes by Modulation of Cyclins Expression.」,生物醫學聯會,Taipei,Taiwan,,2008-03-29
  24. Chuang KA、Tsai WJ、Kuo YC,「Evaluation of anti-leukemia activities of Chinese herbs by beta-catenin reporter gene.」,生物醫學聯會,Taipei,Taiwan,,2008-03-29
  25. Chang CT、Chou SH、Liew YF、Lu CY、Wang SJ、Tzeng WF、Huang S RF、Chou SS P、Kuo YC,「A Bioactive component from Cinnamomum kotoense Regulates Human T Lymphocytes Activation and Proliferation.」,,FIMSA 2008,,,2008-10-17
  26. Ka SM、Ho PJ、Lin YF、Chang DM、Kuo YC、Tsai WJ、Lin YL、Shen CC、Tsai PY、Chen A,「Armepavine has therapeutic effects on autoimmune crescentic glomerulonephritis in a mouse model.」,the 4th Asian Congress on Autoimmunity ,,Singapore,,2009-06-01
  27. Yuh-Chi Kuo、Yueh-Hsiung Kuo 、Yuang-Lian Lin、Wei-Jern Tsai ,「Anti-Herpes Simplex Virus Type 1 Activity of Yatein in Vitro」,World Summit of Antivirals (WSA)-2009,Beijing,China,,2009-07-18
  28. Yan-Cheng Ke、Wei-Jern Tsai、Yuh-Chi Kuo,「Analysis of Anti-Herpes Simplex Virus Type 1 Activity from Prunus zippeliana Miq. and Viscum articulatum Burm. Extracts」,中華民國生物醫學聯會,台北,臺灣,,2009-03-21
  29. Chun-Yi Lin、Wei-Jern Tsai、Yuh-Chi Kuo,「Inducible Nitric Oxide Synthase Gene Expression in Human Microglia Cells Induced with β-Amyloid As A Model for Screening Neuron Protection Lead Compounds」,中華民國生物醫學聯會,台北,臺灣,,2009-03-21
  30. 郭育綺,「丹蔘六種成分對於人類周邊血單核細胞之影響」,耕莘醫院計畫成果報告,台北,臺灣,,2008-11-24
  31. Yang SC、Huang YL、Tsai WJ、Kuo YC,「Regulation of Cell Proliferation in Human Peripheral Blood Mononuclear Cells by 4-Hydroxy-17-methylincisterol Isolated from Agaricus Blazei.」,14th International Congress of Immunology,Kobe,Japan,,2010-08-22
  32. Wang HN、Wu TS、Tsai WJ、Kuo YC,「Study of Coriaria Intermedia Matsum Inhibitory Effects on Herpes Simplex Virus Type 1 Replication.」,生物醫學聯會,台北,臺灣,,2010-03-27
  33. Hunag WC、Lee CK、Tsai WJ、Kuo YC,「Inhibitory Mechanisms of 3,9-Dihydroeucomin from Agave sisalana on human T lymphocytes proliferation induced by anti-CD3/CD28 antibodies.」,生物醫學聯會,台北,臺灣,,2010-03-27
  34. Yu-Zhi Li、Wei-Jern Tsai、Tzong-Huei Lee、Yuh-Chi Kuo,「Investigation of Inhibitory Action Mechanisms of Dimocarpus Longan Flower Extracts on Herpes Simplex Virus Type 1 Replication」,生物醫學聯會,台北,臺灣,中華民國生理學會,2011-03-19
  35. Ya-Ting Chang、Wei-Jern Tsai、Sang-Shing Peter Cho、Shiu-Huey Chou、Yih-Fong Liew、Jyh-Yih Leu、Woan-Fang Tzeng、Rwei-Fen S. Huang、Chia-Chuan Wang、Yuh-Chi Kuo,「Synthetic Piperidine Compounds Regulate Inflammatory Responses in Microglia Cells」,生物醫學聯會,台北,臺灣,中華民國生理學會,2011-03-19
  36. Hui-Ru Leu、Wei-Jern Tsai、Yuh-Chi Kuo,「 Inhibitory effects of leaf extracts from Coriaria intermedia on HSV-1 replication in SH-SY5Y human neuron cells.」,生物醫學年會,台北,臺灣,,2012-03-17
  37. Huang SH、Tsai WJ、Chang WL、Kuo YC,「Analysis of anti-Herpes Simplex Virus type 1 Activities from Polygonum Multiflorum Extracts and Their Effects on Expression of Alzheimer's Disease Marker」,生物醫學聯會,,臺灣,,2013-03-23

國科會研究計畫

  1. 郭育綺,天然物抑制單純庖疹病毒第一型感染之體內藥理活性與作用機轉之探討,2005-08-01~2006-07-01,NSC 94-2323-B-030-001
  2. 郭育綺,探討白花藤有效成分 5-methoxyseselin 藉由調控 NF-AT與NF-kB之活化而影響人類 T 淋巴細胞中細胞週期蛋白與細胞激素基因之表現並其在自體性免疫疾病老鼠體內之藥理活性評估 (2/2),2005-08-01~2006-07-01,NSC 94-2320-B-030-001
  3. 郭育綺,蟬花中有效成份 Ergosterol peroxide 對於 T 淋巴細胞: (I)細胞激素基因表現之調控與 (II)細胞週期進行之影響,2001-08-01~2002-07-31,NSC
  4. 郭育綺,探討蓮子有效成份 (S)-Armepavine 影響 MAP kinases 活化而調控T 淋巴細胞增生與其在動物體內之藥理活性分析 (2-1),2002-08-01~2003-07-31,NSC 92-2320-B-077-019
  5. 郭育綺,探討由小本山葡萄純化之 Amelopsin C 藉由調控單純庖診病毒第一型大分子合成而抑制之複製及以病毒皮膚感染之 BALB/c 小鼠為模式分析其體內藥理活性並以此研究模式提供病毒藥物篩選服務,2003-08-01~2004-07-31,NSC 92-2320-B-030-001
  6. 郭育綺,探討蓮子有效成份 (S)-Armepavine 影響 MAP kinases 活化而調控T 淋巴細胞增生與其在動物體內之藥理活性分析 (2-2),2003-08-01~2004-07-31,NSC 93-2320-B-077-019
  7. 郭育綺,探討nstpbp002646、nstpbp002649 或 nstpbp002652藉由調控單純庖診病毒第一型大分子合成而抑制之複製及以病毒皮膚感染之 BALB/c 小鼠為模式分析其體內藥理活性(NSC93-2323-B-030-001),2004-08-01~2005-07-31,NSC
  8. 郭育綺,探討白花藤有效成分 5-methoxyseselin 藉由調控 NF-AT與NF-kB之活化而影響人類 T 淋巴細胞中細胞週期蛋白與細胞激素基因之表現並其在自體性免疫疾病老鼠體內之藥理活性評估 (1/2),2004-08-01~2005-07-31,NSC
  9. 郭育綺,天然物抑制單純庖疹病毒第一型感染之體內藥理活性與作用機轉之探討(II)藥理機轉分析,2006-08-01~2007-07-31,NSC 95-2323-B-030-001
  10. 郭育綺,黃土樹、台灣馬桑與越南懸鉤子抑制單純疱疹病毒第一型感染之體外與體內藥理活性探討,2008-08-01~2009-07-31,NSC 96-2320-B-030-006-MY3
  11. 郭育綺,黃土樹、台灣馬桑與越南懸鉤子抑制單純疱疹病毒第一型感染之體外與體內藥理活性探討,2007-08-01~2008-07-31,NSC 96-2320-B-030-006-MY3
  12. 郭育綺,抗腫瘤藥物篩選平台HEK293-TOPrep報導基因操作標準流程之建立與去甲基斑蝥素及其它先導藥物體外與體內藥理活性之探討,2009-08-01~2010-07-31,NSC 98-2323-B-030-001-CC1
  13. 郭育綺,黃土樹、台灣馬桑與越南懸鉤子抑制單純疱疹病毒第一型感染之體外與體內藥理活性探討,2009-08-01~2010-07-31,NSC 96-2320-B-030-006
  14. 郭育綺,國科會補助產學合作研究計畫-探討龍眼花免疫調控活性及其有效成分以建立標準產程開發之指標(1/2),2010-02-01~2011-01-31,NSC 99-2622-B-030-001-CC2
  15. 郭育綺,蓮霧葉、蘭嶼肉桂及瓊麻葉中天然物其體內與體外免疫調控活性與作用機轉之探討,2010-08-01~2013-07-31,NSC 99-2320-B-030-004-MY3
  16. 郭育綺,椆櫟柿寄生,大王椰子與何首烏之抗病毒活性研究,2013-08-01~2016-07-31,NSC102-2320-B-030 -003 -MY3

非國科會研究計畫

  1. 郭育綺,探討由小本山葡萄純化之 Amelopsin C 藉由調控單純庖診病毒第一型大分子合成而抑制之複製及以病毒皮膚感染之 BALB/c 小鼠為模式分析其體內藥理活性並以此研究模式提供病毒藥物篩選服務,2003-08-01~2004-07-31
  2. 郭育綺,探討nstpbp002646、nstpbp002649 或 nstpbp002652藉由調控單純庖診病毒第一型大分子合成而抑制之複製及以病毒皮膚感染之 BALB/c 小鼠為模式分析其體內藥理活性(NSC93-2323-B-030-001),2004-08-01~2005-07-31
  3. 郭育綺,探討白花藤有效成分 5-methoxyseselin 藉由調控 NF-AT與NF-kB之活化而影響人類 T 淋巴細胞中細胞週期蛋白與細胞激素基因之表現並其在自體性免疫疾病老鼠體內之藥理活性評估 (1/2),2004-08-01~2005-07-31
  4. 郭育綺、賴金美,94生物技術科技人才培育先導型計畫,教育部輔大,2005-01-01~2005-12-31
  5. 郭育綺,生物科技前瞻性人才培育計畫案,教育部,2005-08-01~2005-12-15
  6. 張西川、郭育綺,探討去甲基斑蝥素之免疫調控活性 (I) 影響人類T 淋巴細胞增生與細胞激素基因表現之評估,台北榮民總醫院,2006-01-01~2006-12-31
  7. 張西川、郭育綺,探討去甲基斑蝥素之免疫調控活性 (Ⅱ) 以全身性紅斑性狼瘡小鼠為模式建立甲基斑蝥素之體內免疫藥理活性,台北榮民總醫院,2007-01-01~2007-12-31
  8. 郭育綺,蓮子有效成分對於自體性免疫疾病老鼠之免疫藥理活性評估,行政院衛生署中醫藥委員會,2005-01-01~2005-12-01
  9. 郭育綺,黑豆多醣體體內與體外免疫調控活性之探討並其保健功能安全性之評估,行政院農業委員會,2005-01-01~2005-12-01
  10. 郭育綺,探討白花藤有效成分 5-methoxyseselin 藉由調控 NF-AT與NF-kB之活化而影響人類 T 淋巴細胞中細胞週期蛋白與細胞激素基因之表現並其在自體性免疫疾病老鼠體內之藥理活性評估 (2/2),2005-08-01~2006-07-01
  11. 郭育綺,天然物抑制單純庖疹病毒第一型感染之體內藥理活性與作用機轉之探討,2005-08-01~2006-07-01
  12. 郭育綺,蓮子有效成份對於自體性免疫疾病鼠之免疫藥理活性評估,衛生署,2005-01-01~2005-12-31
  13. 郭育綺,黑豆多醣體體內與體外免疫調控活性之探討並其保健功能安全性之評估II:體內免疫調控活性之分析,行政院農委會,2006-01-01~2006-12-31,96農科-1.2.1-科-a1
  14. 郭育綺,農業生物技術綜合研究計畫-黑豆多醣體體內與體外免疫調控活性之探討並其保健功能安全性之評估,農委會,2005-01-01~2005-12-31
  15. 郭育綺,蓮子,衛生署中藥,2005-01-01~2005-12-31
  16. 郭育綺,巴西洋菇藉由免疫調控以改善過敏反應、發炎反應與病毒感染之評估並其有效成份之鑑定(3-2),衛生署,2001-08-01~2002-07-31
  17. 郭育綺,蟬花中有效成份 Ergosterol peroxide 對於 T 淋巴細胞: (I)細胞激素基因表現之調控與 (II)細胞週期進行之影響,2001-08-01~2002-07-31
  18. 郭育綺,巴西洋菇藉由免疫調控以改善過敏反應、發炎反應與病毒感染之評估並其有效成份之鑑定(3-3),衛生署,2002-08-01~2003-07-31
  19. 郭育綺,探討蓮子有效成份 (S)-Armepavine 影響 MAP kinases 活化而調控T 淋巴細胞增生與其在動物體內之藥理活性分析 (2-1),2002-08-01~2003-07-31
  20. 郭育綺、陳翰民,生物技術科技教育改進計畫,教育部輔大,2003-01-01~2004-12-31
  21. 郭育綺,探討中藥方劑或中草藥之免疫調控作用,財團法人生物技術開發中心,2003-08-01~2003-12-31
  22. 郭育綺,探討蓮子有效成份 (S)-Armepavine 影響 MAP kinases 活化而調控T 淋巴細胞增生與其在動物體內之藥理活性分析 (2-2),2003-08-01~2004-07-31
  23. 郭育綺,黑豆多醣體體內與體外免疫調控活性之探討並其保健功能安全性之評估(III)藉由生物活性追蹤以建立商品化前製備過程與材料,行政院農委員會,2007-01-01~2007-12-31,96農科-1.2.1-科-a1
  24. 郭育綺,Seselin對於人類T淋巴細胞週期進行,細胞激素基因表現與細胞訊息傳導之調控作用,輔仁大學,2007-04-01~2008-03-31,9991A01
  25. 郭育綺,利用β-Catenin啟動子之報導基因平台評估具抗血癌活性之中草藥,輔仁大學生命科學系,2007-08-01~2007-12-31,CCMP96-RD-207
  26. 郭育綺,黑豆多醣體體內與體外免疫調控活性之探討並其保健功能安全性之評估(IV)商品化製程之開發與其訊息傳導途徑之分析,行政院農業委員會,2008-01-01~2008-12-31,97農科-1.2.1-科-a1
  27. 郭育綺,以多功能藥理活性分析平台評估改善神經退化性疾病之先導藥物,輔仁大學,2008-08-01~2009-07-31,109731040995
  28. 郭育綺,97年度生物及醫學科技人才培育先導型計畫 - 醫衛分子檢驗,教育部,2008-01-01~2008-12-31
  29. 郭育綺,98年度生物及醫學科技人才培育先導型計畫 - 醫衛分子檢驗,教育部,2009-01-01~2009-12-31
  30. 郭育綺、曾婉芳,以多功能藥理活性分析平台評估改善神經退化性疾病之先導藥物,2009-08-01~2010-07-31
  31. 郭育綺,丹蔘中六種化合物對於人類周邊血單核細胞活化增生之影響,耕莘醫院,2007-07-01~2008-06-30,CHT-97-1-2A38
  32. 郭育綺,以多功能藥理活性分析平台評估改善神經退化性疾病之先導藥物,醫學系,化學系,營養科學系,2007-08-01~2008-07-31,9991A15/10973104995-
  33. 郭育綺,龍眼花萃取物NFs多酚神經保護作用之評估,康達生命科學有限公司,2009-06-01~2009-09-15,600028

指導碩博士論文

  1. 郭育綺,蘇德軒,碩士,94,「評估亞美罌粟鹼對於脂多醣在大鼠腎間膈細胞中所誘導發炎性細胞激素表現之抑制效果」
  2. 郭育綺,李秉勳,碩士,94,「由重組桿狀病毒感染之 Sf9 細胞株中表現及純化嚴重急性呼吸道症候群冠狀病毒之 S547 外套膜蛋白」
  3. 郭育綺、蔡維人,楊宗餘,碩士,94,「探討牛蒡子苷元抑制血小板凝集之作用機制」
  4. 郭育綺、蔡維人、廖志飛,劉志鵬,博士,94,「(S)-Armepavine 之體內與體外免疫藥理活性探討」
  5. 郭育綺,李岳錡,碩士,93,「半邊蓮萃取抗單純庖疹病毒地一型活性」
  6. 郭育綺,郭裕民,碩士,93,「蓮霧中Gallomyricitrin抑制人類單核細胞增生」
  7. 郭育綺,楊士杰,碩士,92,「 巴西洋菇中4-Hydroxy-17-methylincisterol 抑制人類周邊寫單核細胞增生」
  8. 郭育綺,許嘉偉,碩士,92,「五倍子之免疫調控作用」
  9. 郭育綺,李亦慶,碩士,92,「黑豆抽出物促進人類周邊寫單核細胞G-CSF產生」
  10. 郭育綺,吳明錫,博士,95,「The polysaccharides from black soybean enhances G-CSF production in BALB/c mice.」
  11. 郭育綺,陳怡君,博士,95,「Norcantharidin inhibits cell cycle progression and cytokines gene expression in human T lymphocytes by modulation of NF-kappa B activation」
  12. 郭育綺,莊凱安,博士,95,「利用 beta-Catenin 啟動子之報導基因平台評估具抗血癌活性之中草藥」
  13. 郭育綺,張筑婷,碩士,96,「於anti-CD28抗體刺激情況下,探討蘭嶼肉桂、牛蒡子及瓊麻中天然物調控人類T淋巴細胞之免疫反應」
  14. 郭育綺,謝繼璋,碩士,96,「大王椰子萃取物抗單純疱疹病毒第一型活性之分析」
  15. 郭育綺,廖芳甫,碩士,96,「探討由蘭嶼肉桂及瓊麻純化之化合物和牛蒡苩元對於脂多醣體誘導大鼠腎間膈細胞中發炎性細胞激素基因表現之抑制作用」
  16. 郭育綺,柯諺呈,碩士,97,「由Prunus zippeliana與Viscum articulatum Burm萃取物中分析抗單純庖診病毒第一型活性」
  17. 郭育綺,林君怡,碩士,97,「利用乙型-澱粉蛋白刺激人類微小膠細胞中 iNOS 基因表現以為神經保護先導藥物篩選模式」
  18. 郭育綺,王心農,碩士,98,「台灣馬桑之抗病毒活性分析」
  19. 郭育綺,黃威程,碩士,98,「天然物之免疫調控活性分析」
  20. 郭育綺,張雅婷,碩士,98,「有機合成化合物對於 C13NJ 細胞免疫反應之影響」
  21. 郭育綺,李昱質,碩士,98,「天然物抗單純庖診病毒第一型活性評估」
  22. 郭育綺,呂蕙茹,碩士,99,「天然物之抗病毒作用分析」
  23. 郭育綺,董毅昱,碩士,103,「中草藥抗病毒活性研究」
  24. 郭育綺,王臆婷,碩士,102,「中草藥之免疫調控活性分析」

獲獎紀錄

  1. 郭育綺,89學年度,行政院國家科學委員會,甲種獎助
  2. 郭育綺,90學年度,行政院國家科學委員會,甲種獎助
  3. 郭育綺,91學年度,行政院國家科學委員會,甲種獎助
  4. 郭育綺,92學年度,行政院國家科學委員會,甲種獎助
  5. 郭育綺,93學年度,行政院國家科學委員會,甲種獎助
  6. 郭育綺,94學年度,行政院國家科學委員會,甲種獎助
  7. 郭育綺,95學年度,行政院國家科學委員會,甲種獎助
  8. 郭育綺,96學年度,國科會,國科會甲種獎助
  9. 郭育綺,97學年度,國科會,國科會甲種獎助
  10. 郭育綺,97學年度,輔仁大學,投稿國際一流期刊論文獎勵
  11. 郭育綺,98學年度,國科會,國科會甲種獎助
  12. 郭育綺,98學年度,輔仁大學,獎勵投稿國際性期刊
  13. 郭育綺,97學年度,輔仁大學,輔仁大學教師及研究人員研究成果獎勵
  14. 郭育綺,97學年度,輔仁大學,97 學年度輔仁大學教師申請校外研究計畫獎勵
  15. 郭育綺,98學年度,輔仁大學,輔仁大學學術研究獎勵
  16. 郭育綺,98學年度,輔仁大學,投稿指標性期刊學術論文獎勵
  17. 郭育綺,98學年度,輔仁大學,98學年度輔仁大學教師研究成果獎勵
  18. 郭育綺,99學年度,輔仁大學,99 學年度投稿指標期刊獎勵 (1)
  19. 郭育綺,99學年度,輔仁大學,99 學年度輔仁大學投稿指標性期刊獎勵 (2)
  20. 郭育綺,99學年度,國科會,99 年度國科會計畫主持人主持費獎勵
  21. 郭育綺,99學年度,輔仁大學,99學年度指標性期刊學術論文獎勵 (3)
  22. 郭育綺,99學年度,輔仁大學,99 學年度指標性論文期刊獎勵 (4)
  23. 郭育綺,99學年度,輔仁大學,2011 輔仁大學研發成果創意商品競賽
  24. 郭育綺,99學年度,輔仁大學,教師教授全英語專業課程獎勵
  25. 郭育綺,100學年度,國科會,國科會計畫主持人獎助
  26. 郭育綺,99學年度,輔仁大學,輔仁大學傑出研究獎
  27. 郭育綺,100學年度,國科會,國科會研究傑出獎勵
  28. 郭育綺,100學年度,國科會,100 年度特殊優秀人才獎勵
  29. 郭育綺,101學年度,輔仁大學,輔仁大學指標性期刊論文獎勵
  30. 郭育綺,101學年度,輔仁大學,指標性期刊論文獎勵

演講

  1. 郭育綺,(S)-Armepavine from Nelumbo nucifera Inhibits Autoimmune Disease of MRL/MpJ-lpr/lpr mice ,輔仁大學 化學系,輔仁大學 化學系,2006-11-02
  2. 郭育綺,Evaluation of Anti-Herpes Simplex Virus Type 1 Infection Agents From Natural Products,輔仁大學 基礎醫學研究所,輔仁大學 基礎醫學研究所,2006-11-30
  3. 郭育綺,Immunomodulatory activities of (S)-armepavine,賽亞基因生技公司,賽亞基因生技公司,2006-11-23
  4. 郭育綺,利用 beta-Catenin 啟動子之報導基因平台評估具抗血癌活性,衛生署中醫藥委員會,衛生署中醫藥委員會,2007-12-18
  5. 郭育綺,The Immunomodulatory Activities of (S)-Armepavine on Autoimmune Diseases in Vivo and in Vitro,杜拜,第一屆藥物開發國際研討會,2008-02-06
  6. 郭育綺,扁柏之抗病毒活性探討,國際抗病毒藥物研討會,北京病毒學會,2009-07-20
  7. 郭育綺,蘭嶼肉桂之免疫調控活性,台北,亞洲免疫學會,2008-10-18
  8. 郭育綺,蓮子免調控活性之作用機轉,台北,長庚大學生物技術研究所,2009-10-20
  9. 郭育綺,黑豆之免疫調控活性,中央大學,中央大學生命科學系,2010-06-01
  10. 郭育綺,EMSA,明志大學化工系,明志大學,2010-10-27
  11. 郭育綺,Chromatin IP,明志大學化工系,明志大學,2010-11-03
  12. 郭育綺,蓮子體外與體內免疫調控活性,輔仁大學營養科學系,輔仁大學營養科學系,2009-03-07
  13. 郭育綺,南台灣中草藥暨機能性食品生技產官學論壇 - 黑豆多醣體之免疫調控活性,台南新營衛生局,台南新營衛生局,2008-12-30
  14. 郭育綺,黑豆多醣體體外與體內藥理活性探討,輔仁大學,醫學院,2010-11-25

專利

  1. 林清淵、林清基、陳建志、郭育綺,從冬蟲夏草(Cordyceps sinensis)分離出具有改善肺功能的活性部份之方法,00582999,2004-04-11~2019-11-17
  2. 莊凱安、郭育綺、蔡維人、呂健惠,一種帶有Wnt訊息活化報導質體之穩定細胞株暨其使用方式與製造方法,I360577,2012-03-21~2028-09-23
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