辜惠君老師

辜惠君老師

職稱: 
助理教授
研究室名稱: 
生技醫藥開發研究室
辦公室位置: 
耕莘樓生命科學系館 LS120U
連絡電話: 
(02)2905-3753
電子信箱: 
141655@mail.fju.edu.tw
學歷: 
台灣大學 藥理學研究所 博士
專長: 
新藥研發
人類疾病致病機轉探討
研究概況: 
天然物開發
人類疾病之實驗動物模式
人類誘導性多功能幹細胞培養
研究方向: 
探討天然物成份與其衍生物活性並應用於新藥研發
探討特定基因在人類疾病中的訊息傳遞路徑

期刊論文

  1. Ku HC, Lee SY, Wu YK, Yang KC, Su MJ*. A Model of Cardiac Remodeling through Constriction of the Abdominal Aorta in Rats. J Vis Exp. 2016 Dec 2;(118).
  2. Ku HC, Lee SY, Lee SS, Su MJ* Thaliporphine, an alkaloid from Neolitsea Konishii, exerts antioxidant, anti-inflammatory, and anti-apoptotic responses in guinea pig during cardiovascular collapse in inflammatory disease. Journal of Functional Food. 2016 July 26; 57-64
  3. Ku HC, Lee SY, Kuo YH*, Yang KC, Su MJ*; Modification of Caffeic Acid with Pyrrolidine Enhances Anti-oxidant Ability by Activating AKT-HO-1 Pathway. PLoS One. 2016 Feb 11(2): e0148545.
  4. Lee SY, Ku HC, Kuo YH, Yang KC, Chiu HL, Su MJ*; Caffeic Acid Ethanolamide Prevents Cardiac Dysfunction by Cardiac Bioenergetic Preservation through Sirtuin Dependent Pathway. Journal of Biomedical Science. 2015 Sep 22: 80.
  5. Lee SY*, Chen CH, Huang GC, Ku HC, Shih SC, Hung LC, Sun FJ, Hsu CP, Ho YH, Tai JH, Lai YL, Chang WH*; Factors associated with attitude and knowledge toward hospice palliative care among medical caregivers. International Journal of Gerontology. 2015 Jun 9; 98-102.
  6. Ku HC, Lee SY, Chen CH, Wang YH, Lin CT, Lee SS, Li TH, Su MJ*; TM-1-1DP exerts protective effect against myocardial ischemia reperfusion injury via AKT-eNOS pathway. Naunyn-Schmiedebergs Archives of Pharmacology. 2015 May 388(5):539-48.
  7. Lee SY, Ku HC, Kuo YH, Chiu HL, Su MJ*; Pyrrolidinyl caffeamide against ischemia/reperfusion injury in cardiomyocytes through AMPK/AKT pathways. Journal of Biomedical Science. 2015 Mar 22: 18.
  8. Ku HC, Su MJ*; DPP4 deficiency preserved cardiac function in abdominal aortic banding rats. PLoS One, 2014 Jan 9(1):e85634.
  9. Ku HC, Chen WP, Su MJ*; DPP4 deficiency exerts protective effect against H2O2 induced oxidative stress in isolated cardiomyocytes. PLoS One. 2013 Jan 8(1):e54518.
  10. Ku HC, Chen WP, Su MJ*; DPP4 deficiency preserves cardiac function via GLP-1 signaling in rats subjected to myocardial ischemia/ reperfusion. Naunyn-Schmiedebergs Archives of Pharmacology. 2011 Aug 384(2):197-207.
  11. Ku HC, Chen WP, Su MJ*. GLP-1 signaling preserves cardiac function in endotoxemic Fischer 344 and DPP4-deficient rats. Naunyn Schmiedebergs Arch Pharmacol. 2010 Dec;382(5-6):463-74.
  12. Chen WP, Tzeng HJ, Ku HC, Ho YJ, Lee SS, Su MJ*.Thaliporphine ameliorates cardiac depression in endotoxemic rats through attenuating TLR4 signaling in the downstream of TAK-1 phosphorylation and NF-κB signaling. Naunyn Schmiedebergs Arch Pharmacol. 2010 Dec;382(5-6):441-53.
  13. 辜惠君。 「醫學新知」DPP4抑制劑的應用。臺大醫院景福醫訊。2014; 31(1):2-4
  14. 辜惠君。 「醫學新知」GLP類新型降血糖藥物與心血管功能調控。臺大醫院景福醫訊。2010; 27(5):2-4。